COVID-19 Metabolomics Datasets

A collection of our manually curated published metabolomics datasets. We appreciate the authors of these studies for sharing their datasets. You can download a data of interest to perform exploratory analysis in MetaboAnalyst. Soon, you will be able to directly explore these datasets in MetaboAnalyst by a simple click.

IDPublicationSample SizeCountryPlatformDownload
1The serum metabolome of COVID-19 patients is distinctive and predictiveCOVID (79); non-COVID (30); Healthy (78)ChinaGC-MSCompound Table
2Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19COVID (139); Healthy (258)USALC-MS/MSCompound Table
3Large-Scale Multi-omic Analysis of COVID-19 SeverityCOVID (102); non-COVID (26)USAGC-MSCompound List
4Covid-19 Automated Diagnosis and Risk Assessment through Metabolomics and Machine LearningCOVID (442); Healthy (350)BrazilDI-MSMass Table
5Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 InfectionCOVID (17); Healthy (25)AustraliaNMRCompound List
6Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19COVID (543); non-COVID (288)USALC-MS/MSCompound Table
7Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severityCOVID (272); non-COVID (67)USALC-MSMass Table
8The COVIDome Explorer researcher portalCOVID (32); non-COVID (32)USALC-MSMass Table
9Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumabCOVID (30); non-COVID (30)AustraliaNMRCompound List
10Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2COVID (103); non-COVID (32); Healthy (26)ItalyGC-MSCompound Table
11The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolismCOVID (53); non-COVID (45)FranceLC-MSCompound Table
12Blood molecular markers associated with COVID-19 immunopathology and multi-organ damageCOVID (46); Healthy (12)ChinaNMRCompound List
13Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkersCOVID (72); non-COVID (27)FranceLC-MSMass Table
14Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discoveryCOVID (20); non-COVID (10)ChinaLC-MSCompound List
15Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patientsCOVID (65); non-COVID (27)MexicoGC-MSCompound List
16Integrated cytokine and metabolite analysis reveals immunometabolic reprogramming in COVID-19 patients with therapeutic implicationsCOVID (44); non-COVID (17); Healthy (20)ChinaLC-MS/MSCompound Table
17Understanding the pathophysiological changes via untargeted metabolomics in COVID-19 patientsCOVID (41); Healthy (44)TurkeyLC-MSMass Table
18Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19COVID (122); non-COVID (39)MexicoLC-MS/MSCompound Table
19Understanding the pathophysiological changes via untargeted metabolomics in COVID-19 patientsCOVID (24); non-COVID (27)ItalyGC-MSCompound Table
20Metabolomic analyses reveals new stage-specific features of the COVID-19COVID (40); Healthy (13)ChinaLC-MS/MSCompound Table
21Cholinergic and lipid mediators crosstalk in Covid-19 and the impact of glucocorticoid therapyCOVID-19 (32); non-COVID (13)BrazilLC-MS/MSMass Table
22The Serum Metabolome of Moderate and Severe COVID-19 Patients Reflects Possible Liver Alterations Involving Carbon and Nitrogen MetabolismCOVID (52); non-COVID (9)ItalyLC-MS/MSCompound Table
23Elevation of Serum Cytokine Profiles and Liver Metabolomic Normalization in Early Convalescence of COVID-19 PatientsCOVID (113); Healthy (10)ChinaLC-MS/MSCompound List
24Immunometabolic signatures predict risk of progression to sepsis in COVID-19COVID (121); non-COVID (37)MexicoLC-MS/MSCompound List
25Metabolic perturbation associated with COVID-19 disease severity and SARS-CoV-2 replicationCOVID (41); non-COVID (31)SwedenLC-MS/MSCompound List
26SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of SerumCOVID (263); non-COVID (280)SpainNMRCompound Table
27Circulating acetylated polyamines correlate with Covid-19 severity in cancer patientsCOVID (76); non-COVID (128)FranceLC-MS/MSCompound Table
28Metabolic and immune markers for precise monitoring of COVID-19 severity and treatmentCOVID (75); non-COVID (9)USANMRCompound Table
29Plasma Markers of Disrupted Gut Permeability in Severe COVID-19 PatientsCOVID (60); non-COVID (20)USALC-MS/MSMass Table
30COVID-19 convalescent plasma composition and immunological effects in severe patientsCOVID (37); non-COVID (16)ColumbiaLC-MSMass Table
31Metabolic snapshot of plasma samples reveals new pathways implicated in SARS-CoV-2 pathogenesisCOVID-19 (27); non-COVID (36)SpainLC-MSCompound Table
32Uneven metabolic and lipidomic profiles in recovered COVID-19 patients as investigated by plasma NMR metabolomicsCOVID-19 (69); non-COVID (71)SpainNMRCompound Table
33Multi-omic profiling of plasma reveals molecular alterations in children with COVID-19COVID (18); Healthy (12)ChinaLC-MS/MSCompound Table
34Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosisCOVID (52); Healthy (43)CanadaGC-MSCompound Table
35Plasma Metabolomic Profiles in Recovered COVID-19 Patients without Previous Underlying Diseases 3 Months After DischargeCOVID (96); Healthy (39)ChinaLC-MS/MSCompound List
36Integrative Metabolomic and Proteomic Signatures Define Clinical Outcomes in Severe COVID-19COVID (330); non-COVID (97)USALC-MSCompound List
37COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal statusCOVID (33); Healthy (16)USALC-MS/MSMass Table
38Kynurenic acid may underlie sex-specific immune responses to COVID-19COVID (39); Healthy (20)USALC-MS/MSMass Table
39Reference data based insights expand understanding of human metabolomesCOVID (15); Healthy (13)BrazilLC-MSMass Table
40Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 PathogenesisCOVID (50); Healthy (26)ChinaLC-MSMass Table
41Proteomic and Metabolomic Characterization of COVID-19 Patient SeraCOVID (65); Healthy (25)ChinaLC-MS/MSCompound Table
42Plasma metabolomic and lipidomic alterations associated with COVID-19COVID (34); Healthy (10)ChinaLC-MS/MSCompound Table
43Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2COVID (103); non-COVID (32); Healthy (26)ItalyLC-MS/MSMass Table
Genome Canada Genome Quebec NIH NSERC CRC
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